This new article shows that stem cells from bone marrow can initiate angiogenisis, or growth of blood cells into islet cells.
Dr Wayne Franco of New Heart LLC reports explosive growth of stem cells capable of becoming islet cells.
FOR IMMEDIATE RELEASE
NEW HEART LLC EXCITED ABOUT ITS UNIQUE STEM CELL
New Heart LLC and its business partner are working with the only adult stem cell that:
1. Can yield naturally up to 12 million stem cells without the use of chemicals (growth factors)
AND 2. Can Transform into cells that secrete insulin
The quantity of stem cells is important because having more stem cells for treatment may be optimal for success.
Cells that secrete insulin are important for having the potential to treat diabetes.
These unique stem cells are obtained from the developing tooth bud (Germ) of wisdom teeth.
Anyone from 7 years – 33 years old who is having their wisdom teeth out should have the wisdom teeth stem cells stored for future use. The ideal age is 7-12 years old before these vital cells undergo further differentiation. Their Neural Crest orgin makes them ideal for numerous treatments.
Anyone with diabetes or a family history of diabetes should consider having their wisdom teeth
INTERESTED IN THIS PROCEDURE? CONTACT:
Dr. Wayne Franco
520 Saybrook Rd
Human BM stem cells initiate angiogenesis in human islets in vitro.
Luo JZ, Xiong F, Al-Homsi AS, Roy T, Luo LG.
Roger Williams Medical Center, Boston University, Providence, RI 02908, USA. Lluo@rwmc.org
BM stem cells may have regenerative effects on islet function through angiogenesis. Human islets (100islet equivalent/mL) were cultured alone (control) or co-cultured (experimental group) with whole human BM (1 × 10(6) cells/mL) for 210 days. A protein array measuring angiogenesis factors found upregulated (experimental vs control, day 210) proteins levels of VEGF-a (535 vs 2 pg/mL), PDGF (280.79 vs 0 pg/mL), KGF (939 vs 8 pg/mL), TIMP-1 (4592 vs 4332 pg/mL) and angiogenin (506 vs 97 pg/mL). Lower protein levels of angiopoietin-2 (5 vs 709 pg/mL) were observed. Depletion of pro-angiogenesis factors in co-culture decreased the effects of BM-induced islet vascularization. Depletion of VEGF-a, eKGF and PDGF significantly reduced islet vascularization but individual depletion of KGF and PDGF had less effects overall on vessel formation. BM-induced vascularization showed significant endothelial cell distribution. Islet vascularization was linked to islet growth. A decrease in islet size indicated poor vascularization. Insulin release was evident in the tissues generated from human islet-BM co-culture throughout the entire culture period. Significant increase in insulin (28.66-fold vs control) and glucagon (24.4-fold vs control) gene expression suggest BM can induce endocrine cell regeneration. In conclusion, BM promotes human islet tissue regeneration via regulation of angiogenesis factors.